A recent study published in Neurology, November 2011, revealed that people in the earliest stages of Alzheimer’s disease are more likely to have a lower body mass index (BMI).
This finding is in accordance with other research stating that people who are overweight in middle age are more likely to develop Alzheimer’s disease decades later than those of a normal weight.
The study assessed persons suffering from mild cognitive impairment as well as individuals with no memory problems. Those who displayed the Alzheimer’s biomarkers were also more likely to have a lower BMI than those who did not.
These results have the potential to incriminate the hypothalamus, the key player in regards to metabolism and food intake, in the development of the disease but the study’s authors noted that further research is needed to assess the direction of cause and effect.